MEDizzy - A 14-year-old girl presents with prolonged bleeding from

Feed Library Learning Discuss Leaderboard Journal

Anemia & Hemorrhagic Disorders

A 14-year-old girl presents with prolonged bleeding from wounds and minor trauma and severe menorrhagia. Family history reveals that her father also has prolonged bleeding from wounds and minor trauma, as does her brother. Which of the following is the most likely mechanism of this patient's disorder?

Explanationvon Willebrand disease, a disorder transmitted by autosomal modes of inheritance (both dominant and recessive) is the most common hereditary bleeding disorder. There are many variants, all marked by either qualitative or quantitative deficiencies of von Wille brand factor.