Questions 25 and 26
A 17-year-old boy is brought to the emergency department after being injured in an automobile accident and sustaining significant blood loss. He is given a transfusion of 3 units of blood to stabilize his blood pressure.
Before the transfusion, which of the following was true about his condition?
ExplanationThe blood loss that occurred in the accident caused a decrease in arterial blood pressure. The decrease in arterial pressure was detected by the baroreceptors in the carotid sinus and caused a decrease in the firing rate of the carotid sinus nerves. As a result of the baroreceptor response, sympathetic outflow to the heart and blood vessels increased, and parasympathetic outflow to the heart decreased. Together, these changes caused an increased heart rate, increased contractility, and increased total peripheral resistance (TPR) (in an attempt to restore the arterial blood pressure).