MEDizzy - The following measurements were obtained in a male

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CARDIOVASCULAR PHYSIOLOGY

The following measurements were obtained in a male patient: Central venous pressure: 10 mm Hg Heart rate: 70 beats/min Systemic arterial [O2] : 0.24 mL O2/mL Mixed venous [O2] : 0.16 mL O2/mL Whole body O2 consumption: 500 mL/min What is this patient’s cardiac output?

ExplanationCardiac output is calculated by the Fick principle if whole-body oxygen (O2) consumption and [O2] in the pulmonary artery and pulmonary vein are measured. Mixed venous blood could substitute for a pulmonary artery sample, and peripheral arterial blood could substitute for a pulmonary vein sample. Central venous pressure and heart rate are not needed for this calculation. Cardiac Output : 500 / 0.24 - 0.16 : 6250 mL/min or 6.25 L/min