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Immunology
A 2-year-old boy presented with failure to thrive, neonatal hypocalcemic seizure, and three attacks of sepsis. Examination reveals cleft palate and holo-systolic murmur. Of the following, the genetic predisposition of this condition is
microdeletions of chromosome 22q11.2
interstitial deletion of the long arm of chromosome 15 (15q11-13)
presence of two copies of paternally derived chromosome 11p15.5
presence of mutated gene on long arm of chromosome 11 (11q22-23)
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Explanation
A. DiGeorge syndrome, 8. Prader_Willi syndrome, C. Beckwith-Wiedemann syndrome,D. Wiskott-Aldrichsyndrome,and E.ataxia-telangiectasia.
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