MEDizzy - A 42-year-old woman, recently diagnosed with lupus

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Corticosteroids and Antagonists

A 42-year-old woman, recently diagnosed with lupus erythematosus, started a therapy with high-dose dexamethasone. Which of the following best explains why synthetic glucocorticoids are usually preferred over cortisol in the therapy of nonendocrine disorders?

ExplanationB Synthetic glucocorticoids are usually preferred over natural hormones for the treatment of nonendocrine disorders because they are less prone to induce salt and water retention w hen given at equivalent anti inflammatory doses.