MEDizzy - A 24-year-old man was admitted to the hospital because of

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ANTINEOPLASTIC DRUGS I

A 24-year-old man was admitted to the hospital because of abdominal discomfort and shortness of breath. The man was diagnosed with testicular cancer 16 month earlier, for which he underwent a radical inguinal orchiectomy. An abdominal computed tomography revealed a 10-cm mass, and a chest radiograph showed multiple nodules in the lung. The first course of a three-drug combination chemotherapy was started. Which of the following drugs was most likely included in the patient’s combination chemotherapy?

ExplanationThe correct answer is D. Testicular cancer is the most common malignancy in men between ages 15 and 35 years. The x-ray and computed tomography results indicate metastatic testicular cancer, and the patient should receive systemic chemotherapy. The combination of cisplatin, etoposide and bleomycin commonly controls the tumor long term and is widely used today. A Carmustine is mainly used for brain tumors. B, C Methotrexate, cytarabine, and mercaptopurine are mainly used for hematologic malignancies.