MEDizzy
MEDizzy
USMLE
Microbiology
A 47-year-old woman comes to the clinic complaining of fever and malaise. She reports having severe headaches associated with some nausea and vomiting, over the past few days. Her urine has been exceptionally dark for the past few days. The patient is mildly jaundiced with scleral icterus. Based on these symptoms the physician suspects hepatitis B and draws blood for serologic testing for hepatitis B markers. If the patient had unprotected intercourse during this infection, the presence of which of the following would be most concerning for her partner?
Explanation
ExplanationB. HBV is transmitted via parenteral, sexual, or maternal-fetal routes. Of the markers listed, only hepatitis B e antigen (HBeAg) signifies active viral replication, and would therefore make transmission of HBV to a partner more likely. HBeAg and hepatitis B core antigen (HBcAg) are antigenic markers of the virus core. They can be detected two-four months after exposure.
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