A 32-year-old woman had been taking a combined oral contraceptive pill for the past 5 years. However, she recently developed a disorder that prompted her physician to withdraw the pill and to recommend other forms of contraception. Which of the following disorders most likely occurred to this patient?
ExplanationEstrogens increase plasma levels of factors II, VII, VIII, IX, X, and XII and are therefore absolutely contraindicated in thromboembolic diseases. Progestin-only contraceptives may be used in women with thromboembolic diseases