MEDizzy - A 43-year-old woman recently diagnosed with endometriosis

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Drugs for Gonadal Disorders

A 43-year-old woman recently diagnosed with endometriosis started a treatment with medroxyprogesterone, one tablet daily. Which of the following effects most likely occurred after a few days of therapy?

ExplanationMedroxyprogesterone is a synthetic progesterone derivative that is about 15 times more potent and has the same pharmacological properties of the parent compound. Progesterone increases the sensitivity of the respiratory center to carbon dioxide, thus leading to an increased ventilatory response. This can explain the measurable reduction of arterial and alveolar carbon dioxide that occurs during pregnancy.