MEDizzy - A 21-year-old man with severe persistent asthma had been on

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Drugs for Bronchospastic Disorders

A 21-year-old man with severe persistent asthma had been on daily inhaled salmeterol, inhaled beclomethasone, and oral zafirlukast for 2 months, with inhaled albuterol as needed. However, his asthma was poorly controlled, and his physician decided to add another drug to the current treatment. Which of the following drugs would be most appropriate for the patient at this time?

ExplanationOral steroids are usually administered to treat severe asthma that is not controlled by other antiasthmatic drugs. Corticosteroids have potent anti inflammatory activity, and although they are not direct bronchodilators, they can relieve bronchial obstruction by improving the responsiveness of β2 receptors to β2 agonists.