MEDizzy
MEDizzy
USMLE
Drugs for Cardiac Failure
A 61-year-old man presented to the hospital with shortness of breath, decreased exercise capacity, and distended neck veins. The man had a history of severe hypertension currently treated with hydrochlorothiazide and captopril. Despite the treatment, his blood pressure was still 170/110. After physical examination and laboratory tests, a diagnosis of diastolic cardiac failure was made. Which of the following would be a useful drug to add to the patient’s therapeutic regimen?
Explanation
ExplanationBeta-blockers are drugs of choice in diastolic heart failure because: • They slow the heart rate, thus allow ing more time for complete ventricular filling. • They increase heart relaxation, thus counteracting the stiffness of the ventricular wall. • They reduce myocardial oxygen demand.
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