MEDizzy - A 47-year-old m an complained of severe pain 3 days after

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Opioid Analgesics and Antagonists

A 47-year-old m an complained of severe pain 3 days after surgery to remove a colon cancer. Physical examination and x-ray confirmed the diagnosis of postoperative adynamic ileus. An analgesic treatment was prescribed. Which of the following analgesic drugs would be contraindicated for this patient?

ExplanationMorphine and other μ (mu) opioid receptor agonists are universally used for the treatment of acute postsurgical pain. However, they have an inhibitory effect on gastrointestinal tract motility and are therefore absolutely contraindicated in treating ileus that can occur mainly after abdominal surgery, as in this case.