MEDizzy - A 45-year-old woman recently diagnosed with lupus

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Pharmacodynamics

A 45-year-old woman recently diagnosed with lupus erythematosus started a treatment with a synthetic steroid. Which of the following is the most likely time lapse expected between receptor activation and therapeutic response?

ExplanationDrugs that activate nuclear receptors to affect transcription usually have a relatively long response time following receptor activation. These drugs regulate gene transcription, which in turn causes an increase or decrease of synthesis of specific proteins. This is consistent with the observation that there is a time lag of hours or days between drug administration and the therapeutic effect of these drugs.