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Obstetric Anesthesia
The P50 for maternal hemoglobin
Increases due to elevated levels of 2,3-diphosphoglycerate (DPG)
Remains unchanged
Increases to maintain pH
Decreases to enhance oxygen delivery to tissues
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Explanation
A. Elevated levels of 2,3-DPG decreases maternal hemoglobin affinity for oxygen, shifting the P50 curve to the right (increasing it from 27 to 30 mm Hg) to enhance oxygen delivery to tissues.
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