The most common cause of an acute hemolytic transfusion reaction is
ExplanationC. Hemolytic reactions occur when the wrong blood type is administered to a patient. The immediate signs of acute hemolytic transfusion reactions include lumbar and substernal pain, fever, chills, dyspnea, flushing of the skin, and hypotension. The appearance of free hemoglobin in plasma or urine is presumptive evidence of a hemolytic reaction. Acute renal failure reflects precipitation of stromal and lipid contents (not free hemoglobin) of hemolyzed erythrocytes in distal renal tubules. Acute hemolytic transfusion reactions are usually due to ABO blood incompatibility, and the most common cause if disidentification of patient, blood transfusion or transfusion unit.
