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Genetics and Metabolism - Set 1
Which of the following would result in Angelman syndrome?
Paternal UPD 15
Maternal UPD 15
A mutation in the SNRPN promoter
Deletion in the paternally derived chromosome 15
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Explanation
Angelman syndrome is caused by loss of a functioning maternally derived chromosome 15. The other listed mechanisms will all cause the Prader-Willi syndrome.
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