MEDizzy
MEDizzy
USMLE
Basic Medicine - Set 26
DNA polymerase can distinguish between dNTPs and rNTPS due to ___________
Explanation
ExplanationDNA polymerase shows an impressive ability of distinguishing between dNTPs and rNTPS. This is facilitated by the steric exclusion of the rNTPS from the DNA polymerase active site which is too small to accommodate the 2’-OH of rNTPs.
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