The formation of the phosphodiester bond is an example of _________ reaction.
ExplanationThe phosphodiester bond is formed in an SN2 reaction in which the hydroxyl group at the 3’ end of the primer strand attacks the α-phosphoryl group of the incoming nucleoside triphosphate. The leaving group for the reaction is pyrophosphate, which arises from the release of the β- and γ-phosphates of the nucleotide substrate.
