Which of the following enzymes is responsible for the digestion of the RNA strand in the RNA-DNA hybrid?
ExplanationWhen making a cDNA library the DNA copy is made from an RNA template thus leading to the formation of the RNA-DNA hybrid. Thus for the production of the chimera molecule the RNA template needs to be hydrolysed which is provided by RNase H enzyme whereas RNase A enzyme removes RNA primer from the in case of replicating the lagging strand.