A 45-year-old woman has a 6-month history of progressive shortness of breath on exertion. She does not smoke. Pulmonary function findings are shown (values are given as % of predicted normal):Vital capacity 60 Forced expiratory volume in 1 second (FEV1) 70 Diffusing capacity for carbon monoxide 50 Maximum voluntary ventilation 60Which of the following most likely explains her limited ability to increase ventilation?