Kawasaki disease (KD) is an acute febrile vasculitic syndrome of early childhood that, although it has a good prognosis with treatment, can lead to death from coronary artery aneurysm (CAA) in a very small percentage of patients. Signs and symptoms
Kawasaki disease produces prolonged fever (often abrupt in onset and preceded by several days of nonspecific symptoms) along with a constellation of clinical features that includes the following:
Irritability
Nonexudative bilateral conjunctivitis (90%)
Anterior uveitis (70%)
Perianal erythema (70%)
Sterile pyuria
Erythema and edema on the hands and feet; the latter impedes ambulation
Strawberry tongue and lip fissures
Hepatic, renal, and GI dysfunction
Myocarditis and pericarditis
Lymphadenopathy (75%); generally, a single, enlarged, nonsuppurative cervical node measuring approximately 1.5 cm.