Video of surgical resection of glioblastoma multiforme, otherwise known as GBM, in a 70+ year old man who presented with confusion and altered mentation. Fluorescein sodium-guided microscopy, and computer navigation and stereotaxy allowed for complete radiographic resection of the tumor with excellent clinical outcome. Courtesy of Dr. Farhad Limonadi, MD from Eisenhower Medical Center. Edited by Camus Yu .