Fowler's syndrome is a syndrome that typically affects women in their 20's. The patients are unable to pass urine normally and they don't feel the urge to empty their bladder when it is full. The severity of the symptoms vary from patient to patient. The cause of the syndrome is still unknown and so is the treatment. The first cases were discussed by professor J Clare Fowler in 1985. In later years it was observed that over half of the patients with the specific disease also suffered from PCOS.