Cardiomegaly This refers to the abnormal enlargement of the heart muscle.This can be attributed to other underlying diseases and is thus a secondary Organveränderung.Der heart muscle must pump more blood volume to provide all the organs with sufficient oxygen.This leads to increased growth of the heart muscle.Translating Factors and / or Ekrankungen are eg: Herzklappenfehler, hyperthyroidism, cardiomyopathy but also extreme physical training (competitive athletes)