What is the most likely cause of this finding in a woman undergoing treatment for breast cancer with spinal metastases? Radiation recall Tinea corporis Lichen simplex chronicus Squamous-cell carcinoma Acute febrile neutrophilic dermatosis
This finding is consistent with radiation recall, in which patients undergoing chemotherapy have sequelae of radiation therapy months to years after the original treatment. The mechanism of radiation recall is unknown but may result from changes in vascularization, impaired epithelial stem cells, or impaired DNA repair