When loading a scalpel blade, the surgeon holds the noncutting portion of the blade in the needle holder and handle, with the male portion of the fitting pointing upward. (B) The surgeon then slides the blade into the handle until it clicks into place. (C) To remove the blade, the surgeon uses the needle holder to grasp the end of the blade next to the handle and lifts it to disengage it from the fitting. (D) The surgeon then gently slides the blade off the handle away from the body and anyone nearby.