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Chronic hyperplastic candidiasis or median rhomboid glossitis

Chronic candidal infections are capable of producing a hyperplastic tissue response (chronic hyperplastic candidiasis). When occurring in the retrocommissural area, the lesion resembles speckled leukoplakia and, in some classifications, is known as candidal leukoplakia. It occurs in adults with no apparent predisposition to infection by C. albicans, and it is believed by some clinicians to represent a premalignant lesion.