Protozoal meningoencephalitis
Mainly caused by Toxoplasma gondii ( protozoa ) First we need to understand definitive and intermediate host Definitive host where sexual reproduction of protozoa occur in host Intermediate host where asexual reproduction of protozoa occur in host PATHOGENESIS 1. Ingestion of contaminated food from cat feces ( oocysts) 2. Oocyst contains bradyzoites 3. Once settle in intestine, oocyst rupture and diffentiate into tachyzoites and gametocytes in definitive host and diifrentiate into only TACHYZOITES in intermediate host 4. Gametocytes fuse into oocyst and excreted in feces on definitive host 5. Tachyzoites infects muscle and brain in intermediate host and redifferentiate into bradyzoites - 6. Disease progress if CELL MEDIATED IMMUNITY IS DOWN IN HOST
