Quincke's disease
A 59-year-old man admitted with an inferior ST-segment elevation MI took no medications no h/o allergies or angioedema Post procedure, a medicine was given later. Diagnosis? Quincke's disease A primary percutaneous coronary intervention was performed, 👉 bare-metal stent was successfully implanted in the circumflex coronary artery. Trt with 6.25 mg of captopril was started 6 hours after completion of the procedure, 👉30 minutes after administration he reported difficulty swallowing and throat pain; 👉lung sounds were normal, and he had no breathing difficulties. uvula was markedly edematous and erythematous *Uvular angioedema, or Quincke's disease, was diagnosed. 👉 treatment with antihistamines and glucocorticoids was started. Isolated uvular angioedema is usually caused by an immediate (type I) hypersensitivity reaction Mast-cell degranulation can occur after exposure to an immunologic or nonimmunologic stimulant. (ACE) inhibitors can cause isolated uvular angioedema although this response to ACE inhibitors is uncommonly important to be aware of it, since it can lead to obstructive respiratory distress if not promptly recognized and treated.