Bulimia may cause numerous serious and even life-threatening complications. Possible complications include: Negative self-esteem and problems with relationships and social functioning Dehydration, which can lead to major medical problems, such as kidney failure Heart problems, such as an irregular heartbeat or heart failure Severe tooth decay and gum disease Absent or irregular periods in females Digestive problems Anxiety, depression, personality disorders or bipolar disorder Misuse of alcohol or drugs Self-injury, suicidal thoughts or suicide