Skinless forearm covered in a plastic bag? The material is actually a dermal matrix called Integra. Integra Dermal Matrix is a two-layer skin regeneration system. The outer layer is made of a thin silicone film that acts as your skin's epidermis. It protects the wound from infection and controls both heat and moisture loss. The inner layer is constructed of a complex matrix of cross-linked fibers. This porous material acts as a scaffold for regenerating dermal skin cells, which enables the re-growth of a functional dermal layer of skin. Once dermal skin has regenerated, the silicone outer layer is removed and replaced with a thin epidermal skin graft. Integra Dermal Matrix is commonly used in the treatment of burns, traumatic wounds, and surgical reconstruction of the skin and underlying tissues.