Provided video gives an overview of the alpha-2 agonist non-catecholamine agents and their various uses in clinical and surgical settings. Timeline: 0:00 - Non-catecholamines alpha-2 agonists (clonidine and alpha-methyldopa 1:41 - Clonidine uses 6:19 - Apraclonidine and brimonidine 7:42 - Central alpha-2 agonists (dexmedetomidine) 9:34 - Guanfacine, guanabenz and tizanidine 11:03 - Summary