Trimethoprim-sulfamethoxazole

Trimethroprim-sulfamethoxazole is a drug combination which acts as inhibitor of the folate synthesis pathway. Since folic acid is an essential vitamin needed for DNA synthesis and various metabolic activities, impairment of this pathway brings cell cycle to a halt. Not only bacteria but protozoa are also affected. Watch this video to learn in detail the pharmacology of this important drug combination. You can also learn about the uses, side effects, warnings and much more. Timeline: 0.00 Overview and formulations 2.43 Dosing 4.20 Uses 5.50 Adverse reactions 8.23 Contraindications 9.51 Drug interactions 10.21 Monitoring 10.38 Mechanism of action 11.10 Warnings 14.16 Doses for different indications