Cirrhosis is a late-stage liver disease in which healthy liver tissue is replaced with scar tissue and the liver is permanently damaged. Watch this video to learn about the pathogenesis of Cirrhosis. 0:00 Introduction 0:18 What is cirrhosis 1:28 End stage CLD 3:47 Causes 4:25 Pathogenesis 10:22 Gross features 11:00 Microscopic features