This detailed video covers the topic of disorders of sexual development, including approach to ambiguous genitalia and all the relevant causes of it that can be described. Timeline: 0:00 - Introduction and objectives 2:17 - Overview of normal sexual development 7:28 - Overview of disorders of sexual development (DSDs) 8:07 - Ambiguous genitalia 9:54 - Sex chromosome DSDs (Turner and Klinefelter syndrome) 12:32 - 46 XY DSD 13:31 - Androgen insensitivity 14:24 - 46XX DSD 15:30 - Congenital adrenal hyperplasia 17:33 - Summary of DSD etiology 18:14 - Approach to ambiguous genitalia (history, examination, investigation, management) 27:31 - Case studies