Simply put, a nosebleed is the loss of blood from the tissue that lines the inside of your nose. Nosebleeds (also called epistaxis) are common. Some 60% of people will have at least one nosebleed in their lifetime. The location of the nose in the middle of the face and the large number of blood vessels close to the surface in the lining of your nose make it an easy target for injury and nosebleeds.