How is hypokalemia treated? If you have a mild case of hypokalemia, your healthcare provider will prescribe a potassium supplement that you’ll take by mouth. If your case is more severe, your healthcare provider may give you potassium through your vein (intravenously). Reasons you may need potassium through your vein include: Your potassium level is extremely low. Hypokalemia is causing abnormal heart rhythms. Supplements taken by mouth aren’t working. You’re losing more potassium than can be replaced with supplements taken by mouth. Your healthcare provider will also treat any condition that’s causing hypokalemia. If you need to take a diuretic, your healthcare provider may switch you to a type that keeps potassium in your body. They may also tell you to take extra potassium supplements