does anyone in here knows what is the pathophysiology of leprosy?? In a simple explanation.
Iprosy is a chronic infection usually caused by the acid-fast bacilli Mycobacterium leprae, which has a unique tropism for peripheral nerves, skin, and mucous membranes of the upper respiratory tract. Symptoms are myriad and include anesthetic polymorphic skin lesions and peripheral neuropathy. Diagnosis is clinical and confirmed by biopsy. Treatment is typically with dapsone plus other antimycobacterial drugs. Patients rapidly become noncontagious after starting therapy.
so how does thd mycobacterium leprae works inside the peripheral nerve??can you explain it to me pls?? Coz i read that there's a schwann cells involved and that CMI thingy. I really need your help. thanks
