Varices are dilated submucosal veins, most commonly detected in the distal esophagus or proximal stomach. Varices are associated with portal hypertension of any cause including presinusoidal (portal vein thrombosis), sinusoidal (cirrhosis) and postsinusoidal (Budd Chiari syndrome) causes the commonest being cirrhosis. Despite advances in therapy over the last decade, variceal hemorrhage is associated with a mortality of at least 20% at 6 weeks.