Our body autonomic system broadly divided into sympathetic and parasympathetic Parasympathetic mediated by cholinergic Sympathetic mediated by cholinergic and adrenergic (adrenaline , norepinephrine, dopamine , dobutamine) There are A1, A2 , B1, B2, B3 receptors for these adrenergic to act Even though the adrenergic agonists are same, BUT IT SHOWS DIFFERENT EFFECT ON DIFFERENT RECEPTOR , RESPECTIVE TO THE PARTICULAR ORGANS, This is very unique, due to different secondary messengers of receptors and also fate of organs ( by cellular diffentation in embryogenesis)