Hemoperfusion refers to the circulation of anticoagulated blood through an extracorporeal circuit with a disposable, adsorbent-containing cartridge (typically activated charcoal or an exchange resin). Two types of hemoperfusion are commonly used: Charcoal hemoperfusion, which has been used to treat liver (hepatic) failure, various types of poisoning, and certain autoimmune diseases when coated with antigens or antibodies.