Sheeza Basharatover 2 years ago

RAS protein mutations

 All Ras proteins are small GTPase involved in transmitting signals within cells.⠀When Ras is 'switched on' by incoming signals, it subsequently switches on other proteins, which ultimately turn on genes involved in cell growth, differentiation, and survival. Mutations in ras genes can lead to the production of permanently activated Ras proteins, which can cause overactive signaling inside the cell, even in the absence of incoming signals, and can lead to the development of cancer.