Iqraabout 2 years ago

Lisch Nodule

Lisch nodules are melanocytic hamartomas that appear as well-defined, dome-shaped elevations projecting from the surface of the iris and are clear to yellow or brown. Segmental disease is caused by late-stage mutations in the NF1 gene during embryogenesis and, in a very limited manner, could explain the development of unilateral Lisch nodules without other clinical characteristics of NF1.