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If you get a hole in your tympanic membrane, it’s called a ruptured eardrum. (Your eardrum separates your outer ear from your middle ear.) Infection, trauma, loud sounds or foreign objects in your ears can cause a ruptured eardrum. In most cases, a ruptured eardrum will heal on its own in a few weeks. But sometimes, it requires surgical repair, such as tympanoplasty.Otosclerosis
Otosclerosis is when abnormal bone remodeling occurs in your middle ear. Bone remodeling is a normal lifelong process in which existing bone tissue replaces itself with new bone tissue. When this process doesn’t go as expected, however, it can cause health problems. With otosclerosis, the tiny bones inside of your middle ear (the malleus, incus and stapes) become hardened and stop vibrating. As a result, sound doesn’t travel properly. Surgery is usually necessary to treat otosclerosis.Epithelial disorderDDX3X Related Developmental DisorderPolycystic Kidney Disease