Diseases of various organ systems can give rise to backache. Following are the condition that can present with back pain: Cardiovascular system: Abdominal aortic aneurysm Respiratory system: Mesothelioma Gastrointestinal system: Pancreatitis or peptic ulcer disease Genitourinary system: Tumors of prostate, ovaries, or testes; pyelonephritis Reference: Bailey and Love's Short Practice of Surgery Image via: https://www.sciencedirect.com/science/article/pii/S0022522302000661