Hello, I studied several articles. It was said that administration of blood products by altering in coagulation state can make DVTs.((This association was amplified in case FFP units are administered. Administration of platelets and cryoprecipitate did not alter this association and indeed their administration was not associated with enhanced risk of DVT development.)) However underline disease and the reason which transfusion is indicated have a great role such as after surgeries and prolong hospitalization.(virchow's triad specially blood stasis because of CBR condition). they suggest that physicians should evaluate accepting lower hemoglobin levels when considering transfusion and/or its dose. Additionally, our FFP finding suggests a potential important role for measures of mechanical clot strength such as rotational thromboelastometry to objectively and more appropriately withhold FFP transfusions given their potential role in DVT development. We speculate that by applying such measures, it may be possible to lower the rate of DVT and its concomitant morbidity. Lastly, the findings of our study advance the development of predictive statistical models of who is at high risk of DVT, and may permit more selective use of chemothromboprophylaxis and avoid the anticoagulant induced risk of hemorrhage in some patients at low risk for DVT Refrence: Ghazi L, Schwann TA, Engoren MC, Habib RH. Role of blood transfusion product type and amount in deep vein thrombosis after cardiac surgery. Thrombosis research. 2015 Dec 1;136(6):1204-10.
Another mechanisms is endothelial injuries which is happen post inflammatory in the cases of sepsis and in patients with inflammatory conditions and comorbidities.
