Dr.ASKYabout 1 year ago

Liquefactive necrosis of the brain

The other important type of necrosis is liquefactive necrosis. The cells are severely damaged not by protein denaturation but by enzymatic degradation. Enzymatic degradation can happen via autolysis/heterolysis. The digestive enzymes enter the cell liquefying the cell hence the name liquefactive necrosis. Examples of liquefactive necrosis are abscesses and necrosis that happen in the brain. What is the reason for liquefactive necrosis in the brain. One reason is that the brain contains the microglial cells which contain a lot of enzymes. These cells when broken down result in the release of these enzymes which cause enzymatic degradation if the cells and tissues and hence resulting in liquefactive necrosis.