Shrutiabout 7 years ago

Xeroderma pigmentosum

It is rare genetic disorder due to defect in DNA repair mechanism (nuclear excision repair) .It is a autosomal recessive disorder.There is severe sunburn after only few minutes in sun ,dry skin,change in skin pigmentation. Treatment-. Avoiding sun, retinoid creams,supplementation of vit D. Prognosis- life expectancy decreased by 30 years.