Pathophysiology of Paediatric COVID-19 In the initial phase, respiratory cells release inflammatory mediators including cytokines. The efficient amount of cytokines induces cytokine storm. It results in macrophage activation syndrome and ARDS. In the second phase, immune dysregulation occurs which result in sepsis-related complications and fatalities. Increase in T lymphocyte infection leads to lymphopenia which ultimately leads to death of child.
Pathophysiology of Paediatric COVID-19 In the initial phase, respiratory cells release inflammatory mediators including cytokines. The efficient amount of cytokines induces cytokine storm. It results in macrophage activation syndrome and ARDS. In the second phase, immune dysregulation occurs which result in sepsis-related complications and fatalities. Increase in T lymphocyte infection leads to lymphopenia which ultimately leads to death of child.
