Castleman disease, also known as Castleman syndrome, is a disorder characterized by excessive cell growth in lymphatic system. This disease can involve single or multiple lymph nodes. The signs and symptoms of Castleman syndrome are similar to that of lymphoma. The patient presents with: - Unexplained weight loss - Fever - Night sweats - Lump in the groin, neck, or axilla - Fatigue and weakness - Splenomegaly - Hepatomegaly - Anemia - Decreased appetite Reference: https://my.clevelandclinic.org/health/diseases/17920-castleman-disease Image via: https://www.jaad.org/article/S0190-9622(10)00029-0/fulltext